American scientists have conducted a large-scale study that has revealed new aspects of the human aging process. Observing volunteers aged 25 to 75, the researchers discovered that aging does not occur gradually, but rather in waves, with two main peaks of change: around 44 and 60 years. This was reported by "Rossiyskaya Gazeta" with reference to The Guardian.
Professor Michael Snyder of Stanford University, who led the study, said: "We're not just changing gradually over time. There are some really dramatic changes."
During the experiment, scientists regularly analyzed blood samples, skin swabs, and mucous membranes from 108 volunteers over several years. They studied more than 135 000 different molecules and microorganisms, including RNA, proteins, metabolites, and various bacteria.
An unexpected discovery was the first peak of changes around age 44, which was observed in both women and men. These changes affected molecules related to the cardiovascular system and metabolism of various substances. The second peak, around age 60, was characterized by changes in molecules responsible for immunity, carbohydrate metabolism, and kidney function.
These findings are consistent with previous research showing a sharp increase in the risk of age-related diseases such as Alzheimer's and cardiovascular disease after age 60. The researchers also suggest the possibility of a third peak of change around age 78, based on previous data.